Author: gene_x

Abstract: To provide a more detailed explanation of how to define promoter types based on the frequency and distribution of the 'GRGGC' motif on both + and - strands within the promoter region, I will outline t

Author: gene_x

Abstract: To generate a database file for the hg38 human genome assembly for use with the DiffReps tool, you will first need to download the hg38 annotation file in GTF or GFF format, and then convert it to the

Author: gene_x

Abstract: H3K4me3（trimethylated histone H3 lysine 4）和H3K27me3（trimethylated histone H3 lysine 27）是组蛋白修饰的一种，与基因表达调控密切相关。转录因子（transcription factor）则是一类能够调控基因转录的蛋白质。 1. H3K4me3：通常与基因启动子区域相关联，标记着活性染色质，有利于基因的转录。H3K

Author: gene_x

Abstract: DESeq2 is a popular method for differential expression analysis of count data from RNA-seq experiments. It estimates fold changes and tests for differential expression using a negative binomial genera

Author: gene_x

Abstract: #https://charlesjb.github.io/How_to_extract_promoters_positions/ setwd("/media/jhuang/Elements1/Data_Denise_LT_DNA_Bindung") # Load required libraries library(TxDb.Hsapiens.UCSC.hg38.knownG

Author: gene_x

Abstract: 1. Identify the overlapping peaks of H3K27ac and H3K4me1 using tools like BEDTools intersect or HOMER mergePeaks. H3K4me1 (histone H3 lysine 4 monomethylation) is commonly found in both active and poi

Author: gene_x

Abstract: H3K27me3 (histone H3 lysine 27 trimethylation) and H3K4me3 (histone H3 lysine 4 trimethylation) are histone marks associated with gene repression and activation, respectively. While these marks can pr

Author: gene_x

Abstract: As of our best knowledge, the following are some of the top sequencing companies in the genomics industry. 1. Illumina: A leading provider of DNA sequencing technologies, with platforms such as NovaS

Author: gene_x

Abstract: [Download python3 script for generating the plot](/static/python/draw2.py "python3 script for generating the plot") [Download raw data 1 for generating the plot](/static/csv/merged_df_26PCs.csv "raw

Author: gene_x

Abstract: 1. RNA Sequencing: RNA sequencing (RNA-Seq) is a technique used to study the transcriptome, or the complete set of RNA molecules expressed within a cell or tissue. This approach allows researchers to